Brice's practice is concentrated on haunting and emotive portraiture. She references art history, images of women in the media and photographs she has taken herself. Brice's work was recently included in the much lauded exhibition ‘Making and Unmaking' curated by Duro Olowu, at Camden Arts Centre in London last year.
In 2018 Lisa Brice had a solo exhibition at Tate Britain as part of their Art Now series. Other solo exhibitions include ‘Well Worn', Goodman Gallery, Johannesburg, South Africa (2015); ‘Cut Your Coat', French Rivera, London, UK (2014).
Notable group exhibitions include: ‘La Diablesse' Tramps, London, UK‘ (2016), ‘Home Truths: Domestic Interior in South African Collections' curated by Michael Godby, South African National Gallery, Cape Town, South Africa (2016), ‘Making & Unmaking', Camden Art Centre, London, UK (2016), ‘New Revolutions', Goodman Gallery, Cape Town, South Africa (2016),‘Puppet Show', curated by Tom Bloor and Celine Condorelli, Gavle Konstcentrum, Kultur & Fritid Gavle, Sweden, toured to Grundy Art Gallery, Blackpool, UK (2014).
Brice's works are included in prominent collections internationally, including: Smithsonian National Museum of African Art, Washington DC, USA; BHP Billiton Collection, Johannesburg, South Africa; SABC Collection, South Africa; Johannesburg Art Gallery, Johannesburg, South Africa; South African National Gallery, Cape Town, South Africa; Michaelis Cabinet, University of Cape Town, South Africa; Gallery Frank Haenel, Frankfurt, Berlin, Germany; South African High Commission, London, England; Sindika Dokolo - African Collection of Contemporary Art, Luanda, Angola.